Publikationen

  • McMillan BJ, Tibbe C, Jeon H, Drabek AA, Klein T, Blacklow SC (2016). Electrostatic Interactions between Elongated Monomers Drive Filamentation of Drosophila Shurb, a Metazoan ESCRT-III Protein. Cell Rep. 2016 Aug2; 16(5):1211-7 doi: 10.1016/j.celrep.2016.06.093. Epub 2016 Jul 21. undefinedpubmed
  • Drusenheimer N., Migdal B., Jäckel S., Tveriakhina L., Scheider K., Schulz K., Gröper J., Köhrer K., Klein T. (2015). The Mammalian Orthologs of Drosophila Lgd. CC2D1A and CC2D1B, Function in the Endocytic Pathway, but Their Individual Loss of Function Does Not Affect Notch Signalling. PLoS Genet. 2015 Dec 31;11(12):e1005749.doi:101371/journal.pgen.1005749. eCollection 2015. undefinedpubmed
  • Gomez-Lamarca M, Snowdon LA, Seib E, Klein T, Bray S. (2015). Rme-8 depletion perturbs Notch recycling and predisposes to pathogenic signaling. J Cell Biol. 2015 Aug 3;210(3):517.doi:10.1083/jcb.20141100107172015c.No abstract available. PMID;26240186.
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  • McMillan BJ, Schnute B, Ohlenhard N, Zimmermann B, Miles L, Beglova N, Klein T, Blacklow SC. (2015). A tail of two sites: a bipartite mechanism for recognition of notch ligands by mind bomb E3 ligases. Mol Cell. 2015 Mar 5;57(5):912-24. doi:10.1016/j.molcel.2015.01.019 Erratum in: Mol Cell. 2015 Apr 16;58(2):387. PMID:25747658.undefinedpubmed
  • Morawa KS, Schneider M. Klein T. (2015). Lgd regulates the activity of the BMF/Dpp signalling pathway during Drosophila oogenesis. Development. 2015 Apr 1;142(7);1325-35, doi: 10.1242/dev.112961. PMID: 25804739.undefinedpubmed
  • Troost, T., Schneider M. and Klein, T. (2015). A re-examination of the selection of the  selection of the sensory organ precursor of the bristle sensilla of Drosophila melanogaster. PLoS Genet. 2015 Jan 8; 11 (1):e1004911. doi:10.1371/journal.pgen.1004911, eCollection 2015.undefinedpubmed
  • Yousefian J., Troost T., Grawe F., Sasamura T., Fortini M. and Klein, T., Dmon 1 controls recruitment of Rab7 to maturing endosomes in Drosophila. J. Cell Sci. ; doi: 10.1242/jcs.114934 (2013)
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  • Schneider, M., Troost, T., Grawe, F., Martinez-Arias, A. and Klein, T. (2012). Activation of Notch in lgd mutant cells requires the fusion of late endosomes with the lysosome. J Cell Sci. 2013 Jan. 15;126(Pt 2):645-56. doi: 10.1242/jcs. 116590. Epub 2012 Nov. 23.undefinedpubmed
  • Troost, T. and Klein, T. (2012). Sequential Notch Signalling at the Boundary of Fringe expressing and Non-expressing cells. PLoS One, 7.undefinedpubmed
  • Troost, T. Jäckel, S. Ohlenhard, N. und Klein T. (2012). The tumor suppressor Lethal (2) giant discs (Lgd) ist reaquired for the function of the ESCRT-III component Shrub/CHMP4. JCS, 125, 763-776
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  • Fiuza, U-M., Klein T. Marinez-Arias, A. und Hayward, P. (2010). Mechanism of ligand mediated inhibition in Notch signaling activity in Drosophila. Dev. Dyn., 798-805 undefined Pubmed
  • Kaspar M, Schneider M, Chia W, Klein T. Klumpfuss is involved in the determination of sensory organ precursors in Drosophila. Dev. Biol. 2008; 324, 177-191 undefinedPubmed
  • Geffers I., Serth K., Chapman G., Jaekel R., Schuster-Gossler K., Cordes R., Sparrow D.B., Kremmer E., Dunwoodie S.L., Klein T., and Gossler A. Divergent functions and distinct localization of the Notch ligands DLL1 and DLL3 in vivo. Journal of Cell Biology 2007 Jul; 178, 465-476
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  • Klein T. (2007). Immunolabelling of imaginal discs. In: Methods in Molecular Biology, Volume: Drosophila, ed. Christian Dahmann Humana Press 2006
  • Jaekel R. and Klein T. The Drosophila Notch inhibitor and tumour suppressor gene lethal (2) giant discs encodes a conserved regulator of endosomal trafficking. Dev. Cell 2006 Nov; 11, 655-669
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  • Kaspar M. and Klein T. Functional analysis of murine CBF1 during Drosophila development. Dev. Dyn. 2006 Apr; 9, 18-27undefinedPubmed
  • Kölzer S. and Klein T. Regulation of expression of Vg and establishment of the dorsoventral compartment boundary in the wing imaginal disc by Suppressor of Hairless. Dev. Biol. 2006 Jan; 289, 77-90 undefinedPubmed
  • Klein T. Notch-pathway. Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine.
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  • Kölzer S, Fuss B., Hoch M. and Klein T. The homeobox transcription factor encoded by the defective ventriculus (dve) gene is required for pattern formation along the proximo-distal axis, cell proliferation and formation of veins in the Drosophila wing. Development 2003 Sep; 130, 4135-4147 undefinedPubmed
  • Klein T. The tumour suppressor gene l(2)giant discs is required to restrict the activity of Notch to the dorsoventral boundary during Drosophila wing development. Dev. Biol. 2003 Mar; 255(2):313-33
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  • Koelzer S, Klein T. A Notch-independent function of Suppressor of Hairless during the development of the bristle sensory organ precursor cell of Drosophila. Development 2003 May; 130(9):1973-88
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  • Klein T. Kuzbanian is required cell autonomously during Notch signalling in the Drosophila wing. Dev. Genes. Evol. 2002 Jun;212(5):251-5. Epub 2002 Apr 20 undefinedPubmed
  • Klein T. Wing disc development in the fly: The early stages. Curr. Opin. Gen. Dev. 2001 Aug; 11, 470-475 undefinedPubmed
  • Klein T., Seugnet L., Haenlin M., Martinez Arias A. Two different activities of Suppressor of Hairless during wing development in Drosophila. Development 2000 Aug; 127(16):3553-66 undefinedPubmed
  • Lawrence N., Klein T., Brennan K., Martinez Arias A. Structural requirements for notch signalling with delta and serrate during the development and patterning of the wing disc of Drosophila. Development 2000 Jul; 127(14):3185-95 undefinedPubmed
  • Brennan K., Klein T., Wilder E., Arias AM. Wingless modulates the effects of dominant negative notch molecules in the developing wing of Drosophila. Dev. Biol. 1999 Dec 1; 216(1):210-29
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  • Bishop S.A., Klein T., Arias AM, Couso J.P. Composite signalling from Serrate and Delta establishes leg segments in Drosophila through Notch. Development 1999 Jul; 126(13):2993-3003 undefinedPubmed
  • Klein T., Arias AM. The vestigial gene product provides a molecular context for the interpretation of signals during the development of the wing in Drosophila. Development 1999 Feb; 126(5):913-25
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  • Klein, T., Couso J.P. and Martinez-Arias A. Wing development and specification of dorsal cell fates in the absence of apterous in Drosophila. Current Biology 1998 Mar; 8, 417-420 undefinedPubmed
  • Klein T., Arias AM. Interactions among Delta, Serrate and Fringe modulate Notch activity during Drosophila wing development. Development 1998 Aug;125(15):2951-62 undefinedPubmed
  • Klein T. and Arias AM. Different spatial and temporal interactions between Notch, wingless, and vestigial specify proximal and distal pattern elements of the wing in Drosophila. Dev. Biol. 1998 Feb 15; 194(2):196-212 undefinedPubmed
  • Klein T. and Campos-Ortega J.A. Klumpfuss a Drosophila gene encoding a member of the EGR family of transcription factors, is involved in bristle and leg development. Development 1997 Aug; 124, 3123-3134 undefinedPubmed
  • Yang X., Bahri, S., Klein T. and Chia W. Klumpfuss, a putative EGR-1 family transcription regulator, acts to differentiate between the identities of two secondary progenitor cells within one neuroblast lineage. Genes. Dev. 1997 Jun; 11, 1396-1408 undefinedPubmed
  • Klein T., Brennan K. and Arias AM. An intrinsic dominant negative activity of serrate that is modulated during wing development in Drosophila. Dev. Biol. 1997 Sep; 189(1):123-34
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  • Hart K, Klein T. and Wilcox M. A minute encoding a ribosomal protein enhances wing morphogenesis mutants. Mech. Dev. 1993 Oct; 43, 101-110 undefinedPubmed
  • Klein T. and Campos-Ortega J. A. Second-site modifier of the Delta wing phenotype in Drosophila melanogaster. Roux's Arch. Dev. Biol. 1992 Dec; 202, 49-60 undefinedSpringerlink
  • Klein T. and Briegleb W. Bau, Funktion und Leistung des Vestibularsystems: Vergleich von Wasser-und Landvertebraten Institut für Flugmedizin, DLR 1988; IB 316-88-03
Verantwortlich für den Inhalt: E-Mail sendenProf. Dr. Thomas Klein